CBD Oil For Pain

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Are you looking for the best CBD oil for pain relief? Learn more about CBD as a potential natural helper for chronic, inflammatory or sports-related pain. CBD oil is a popular natural solution for many types of aches and pains. In this guide, we cover the top 5 CBD oil brands for pain and explain how this supplement can help with your condition. Scientists have tested CBD’s efficacy as an analgesic—and with promising results. Here’s what we know so far about how we can use CBD oil for pain relief.

Best CBD Oil for Pain: 10 Products Review

Are you searching for the best CBD oil for pain relief? If you’re interested in CBD oil for pain relief, it’s essential to know what to look for, which can be hard when so many products are flooding the market. That’s why we’ve put together a list of the 10 best CBD oils for pain relief, based on our research and the feedback from other CBD users.

CBD oil is becoming increasingly popular as a natural remedy for various health conditions, including pain relief. It’s mainly become a favorite amongst those who deal with chronic pain looking for a natural solution for comfort without using opioids or other drugs that can have harmful side effects.

CBD, or cannabidiol, is a compound found in the cannabis plant. Unlike its more famous counterpart, THC, CBD is not psychoactive, meaning it won’t get you high. However, it still affects the body positively by reducing inflammation and pain signals sent to the brain. CBD is well known for its pain-relieving benefits and its many other uses.

Top 10 Best CBD Oils for Pain

  1. Joy Organics – Best Overall CBD Oils for Pain
  2. Green Roads – Runner Up
  3. CBDistillery – Honorable Mention
  4. Koi CBD – Flavor Variety
  5. CBDfx – Great Reputation
  6. Kanibi – Informative
  7. Extract Labs – Vegan-Friendly
  8. Receptra Naturals – Best Full-Spectrum CBD Oil for Pain
  9. Tanasi – Additional Terpenes
  10. Hempsi – Beneficial Cannabinoids

Best CBD Oils for Pain: Top 10 Products

  1. Best Certified Organic Option – Joy Organics

In 2018, a woman named Joy Smith and her family started Joy Organics. She learned about CBD after having problems with pain and sleep, and she wanted to see if it could help her too. She was driven to discover CBD products that really worked and eventually decided to start her own company. The brand now offers a range of broad- and full-spectrum CBD products that are third-party tested and certified organic.

CBD oils for pain-relieving effects include:

  • Broad-spectrum CBD oil – 5 flavor options
  • Full-spectrum CBD oil – 2 flavor options

Joy Organics tests all of its products using a third-party lab and makes those results available to its customers. They also use CBD extracted from US-grown organic hemp using a clean CO2 extraction process. Their products are also certified organic by the US Hemp Authority. In addition, their oils come in various potencies and flavors, making it easy to find the perfect product for you.

What Customers Say:

Customers seem very satisfied with Joy Organics, with many people saying these oils have helped with their pain, anxiety, and sleep. They appreciate that the oils are certified organic and third-party tested, and they find the customer service to be very helpful.

  • USDA-certified organic
  • Plenty of options for flavor
  • Wide potency range
  • Vegan
  • 90-day money-back guarantee
  • International shipping unavailable

Green Roads CBD was founded by a pharmacist with over 20 years of experience, and they are dedicated to helping people find health and well-being through the power of plants. All their products are third-party tested to ensure quality and potency, and they commit to customer satisfaction.

Green Roads CBD offers a wide range of products that can be used to promote natural pain relief, and they are constantly innovating to bring new and better products to their customers. Green Roads CBD is a great option if you’re looking for a brand that you can trust.

The best CBD oil from Green Roads includes:

  • Full-spectrum (unflavored) CBD oil
  • Broad-spectrum (unflavored and flavored) CBD oil

Green Roads CBD oil is available in various potencies and flavors so that you can find the perfect product for your needs. Their oils are made with either broad-spectrum or full-spectrum CBD, and they use a CO2 extraction process to ensure purity and potency.

Their CBD oil is also third-party tested for safety and quality, and they provide a money-back satisfaction guarantee.

What Customers Say:

Green Roads seems to be a favorite among customers when it comes to CBD products. People appreciate how quickly it works, promoting calmness without making them drowsy. The taste is also noteworthy—it’s great without being too intense or overwhelming.

Pain relief is another big selling point, with many people saying it’s helped them find relief when other medications haven’t done the trick. Overall, Green Roads CBD is a reliable and effective option for anyone looking to try CBD products.

  • Different potency options
  • Flavor options
  • Third-party tested
  • Pharmacist-formulated
  • Generous discounts available
  • No flavor options for full-spectrum CBD oil

CBDistillery was founded in Colorado in 2016 with a mission to make high-quality CBD oil and other products available to as many people as possible. They use only natural ingredients in their CBD products, and third-party lab results are available on their website for every customer. In addition, CBDistillery is committed to transparency and accuracy throughout every step of the CBD manufacturing process.

You’ll only find the best CBD oil offered by CBDistillery, including:

  • Full-spectrum CBD oil – flavored and unflavored
  • Nighttime CBD oil with added CBN

CBDistillery offers a wide range of full-spectrum CBD oils and gummies in various potency and flavor options. So whether you’re looking for a milder dose of CBD to help with everyday aches and pains after physical activity, or you’re seeking other pain relief, they have an oil that’s right for you. And because their products are derived from US-grown hemp, you can be confident that they’re of the highest quality and purity.

What Customers Say:

CBDistillery is one of the leading CBD brands on the market, and for a good reason. Their products are effective, their customer service is top-notch, and their prices are unbeatable. But don’t just take our word for it—we read hundreds of reviews and saw that customers were reaping the benefits.

Among these reviews, people claimed CBDistillery’s oils were better than previously tried brands, helped promote a good night’s sleep, and eased pain fast. They also noted that customer service was fantastic and delivery time was fast.

  • Bundles available
  • 60-day money-back guarantee
  • Great customer service
  • Flavor options
  • Non-GMO ingredients
  • Third-party tested
  • Cost of shipping is not included in the money-back guarantee

Koi was founded in 2015 and believes that everyone should have access to the highest-quality CBD oil available. They believe that attention to detail and using quality ingredients are the key to providing the most consistent and refined CBD oil on the market. In addition, every batch of their CBD has full traceability from start to finish, so you can be sure that you’re getting the purest, most potent CBD oil product possible.

Oils offered by Koi CBD include:

  • Full-spectrum oil – 6 flavor options
  • Broad-spectrum oil – 6 flavor options

Koi offers a variety of CBD oils in multiple flavors and potency options. Whether you’re looking for broad-spectrum or full-spectrum CBD oil, they’ll have what you’re looking for. And because this company wants you to be confident in your purchase, all of their CBD oils are third-party tested for purity and potency.

What Customers Say:

Koi has hundreds of positive reviews raving about how well their CBD oils worked for their pain and other ailments. Some customers said these products helped them relax and focus without causing drowsiness. Other reviews claimed the flavor options were great and customer service was excellent.

  • Several great flavor options
  • Broad- or full-spectrum available
  • Third-party tested
  • Money-back guarantee
  • Good customer support
  • Might be too expensive for some

CBDfx is one of the most well-known and reputable CBD brands on the market. The company was founded in 2014 in California to make CBD oil more accessible to everyone. CBDfx is committed to producing high-quality CBD products and focuses on transparency, ensuring that their customers know exactly what they’re getting.

The company offers a wide range of CBD products, including CBD oil tinctures, oils, and capsules. Whether you’re looking for pain relief or just want to try CBD for the first time, CBDfx has something for everyone. CBDfx is a brand you can trust with its commitment to quality and transparency.

Some of the best CBD oil offered by CBDfx include:

  • Broad-spectrum oil – flavored or unflavored
  • Calming, Wellness, and Sleep tinctures

CBDfx’s CBD oil for pain uses only the highest-quality ingredients and comes in various potencies to meet your needs. Their broad-spectrum CBD oil helps your body to experience the entourage effect, which increases the overall benefits of CBD. You can also add CBN, THC, or melatonin to your oil to address multiple issues at once. So whether you need a low dose for general wellness or a higher potency for more severe pain relief, CBDfx has an option for you. And their convenient online ordering makes it easy to get the relief you need.

What Customers Say:

CBDfx has thousands of happy customers who are highly satisfied with their purchases. Reviews say that the customer service is excellent and that the tinctures help them sleep better at night. They also appreciate the great taste of the product and how it helps with pain and mood. Overall, people are thrilled with CBDfx and would recommend their products to others.

  • Wide variety of oils
  • Flavor options
  • Gluten-free and organic hemp
  • Great taste
  • Customer service can be slow at times

While Kanibi is newer to the CBD scene, they make up for it with their dedication to quality and ethics. They offer a diverse line of full-spectrum CBD and isolate (pure CBD oil) products built on scientific evidence and high-quality ingredient standards. Their dedication to constant improvement can be seen in their policy of double third-party testing of each product batch to ensure the highest quality possible.

Oils offered by Kanibi include:

  • Full-spectrum CBD oil – 6 flavor options
  • CBD isolate – 3 flavor options
  • CBD + CBN – peppermint flavor

Kanibi offers a wide range of CBD oil products made with CBD isolate and full-spectrum oil. They use CO2 extraction methods and are GMP-certified. Their oils come in several flavors, with multiple potency options, making it easy to find the perfect product for you.

What Customers Say:

Kanibi has built a name for itself through thousands of satisfied customers voicing their positive reviews. Some of the most common benefits buyers report are that these oils have improved their sleep, reduced anxiety, and provided excellent pain relief. People also appreciate the wide variety of flavors and potencies to choose from. Customers also note that customer service is responsive, and they appreciate that there are no artificial ingredients.

  • Informative website
  • Double third-party tested
  • Organic
  • CO2 extraction methods
  • Interest-free payment plan available
  • On the expensive side

Extract Labs is a company founded by veterans which focuses on delivering the best CBD products to their customers. By providing third-party lab results on its website, the brand strives to make the information as accessible as possible. All ingredients are high-quality and organic, and all of their hemp seed oil is produced in the United States from US-farmed and organic hemp.

Oils offered by Extract Labs include:

  • Full-spectrum CBD oil – 9 formula options
  • Broad-spectrum CBD oil – 9 formula options
  • CBD isolate – 9 formula options

All Extract Labs CBD oil is made with organic, non-GMO hemp grown in the United States. Extract Lab offers a wide range of potencies of full-spectrum CBD oil, broad-spectrum CBD oil, and CBD isolate.

Depending on your pain relief needs, you may select from various oils with added therapeutic components like terpenes or vitamins. Each batch is third-party tested, and those results are made available to view on the company website.

What Customers Say:

Customers seem widely pleased with their purchases from Extract Labs, with many voicing their satisfaction with the products they tried. The most common praise these CBD oils have received is that the wide variety of formulas help people tackle multiple issues at once, such as combating pain while boosting the immune system. Customers are also pleased by the potency options and the fact that the website provides easy access to third-party lab results.

  • Vegan formula
  • Wide variety
  • Third-party tested
  • Natural and gluten-free ingredients
  • Organic, non-GMO hemp
  • No money-back guarantee

Receptra Naturals is a CBD company known for the quality of its hemp plants and clean process from start to finish. They only use flowers grown on their family-owned farm, which are self-grown and hand-picked. Their products are all plant-based and organic, so you know you’re getting top-quality CBD oils.

The best CBD oils for pain from Receptra Naturals include:

  • Serious Relief + Turmeric 0% THC Tincture: Contains 33 mg of CBD per dose
  • Serious Relief + Turmeric Tincture: Contains 66 mg of CBD per dose
  • Serious Relief + Turmeric Tincture: Contains 33 mg of CBD per dose

Receptra Naturals CBD oils contain more than just CBD. First, the CBD itself is full-spectrum CBD, so you’re getting all the benefits of the entire hemp plant. In addition, Receptra adds other beneficial oils, including MCT oil and avocado oil, and other omega acids, to provide you with overall wellness benefits.

These CBD oils are effective in relieving pain fast and helping you get back on your feet in no time.

What Customers Say:

Receptra customers rave about how quickly the company’s CBD oils for pain work and how effective they are for various issues. Many customers have made Receptra CBD oils part of their daily routine as a healthier and more natural solution for pain relief. Some customers have also found these oils effective for their elderly family members, helping with pain caused by arthritis, old injuries, and more.

  • Partners with charities
  • Free shipping
  • 30-day satisfaction guarantee
  • Premium quality products
  • Discounts on bundles
  • Not a lot of information about the company’s extraction methods

Based in Tennessee, Tanasi is dedicated to providing CBD products that promote healthy living based on science. The brand is committed to making high-quality, scientifically backed products that customers can trust. Tanasi shows its commitment to its mission by partnering with Middle Tennessee State University to research the best CBD extraction methods possible.

Tanasi offers a full-spectrum CBD oil to help with pain in both an unflavored or blueberry flavor.

Tanasi’s full-spectrum CBD oils are made with a formula developed by two scientists at the Middle Tennessee State University that improves the bioavailability of the CBD. Better bioavailability means your body can absorb more of the beneficial cannabinoids in this oil than in other brands.

There are various potencies available to help you tailor your treatment to your specific needs. All products are made with organic ingredients and do not contain artificial sweeteners or flavors.

What Customers Say:

Customers report high satisfaction with Tanasi’s CBD oils, citing the product’s effectiveness in treating various conditions like chronic pain, anxiety, and insomnia. Many also appreciate the wide range of potencies available and the fact that the oil comes in an unflavored option that has a mild taste. The added terpenes are also a popular feature, as they provide an extra boost of therapeutic benefit.

  • Developed by scientists
  • Improved bioavailability
  • Added beneficial terpenes
  • Third-party tested
  • Fast-acting
  • Limited flavor options

Hempsi is an Oregon-based company that uses a proprietary growing and extraction process that ensures that its CBD oils lock in the fullest array of cannabinoids and terpenes. The company farms its hemp and ensures quality by overseeing everything from planting to bottling. Hempsi is also committed to sustainability and only uses recyclable materials in its packaging.

The full-spectrum Live Oil produced by Hempsi is made with vegan and non-GMO ingredients. The entourage effect provided by this oil’s vast array of cannabinoids and terpenes is further enhanced by Hempsi’s unique extraction process that they say captures more beneficial compounds than other brands. The oil is also third-party tested for potency and safety.

What Customers Say:

Customers report feeling the effects of Hempsi’s Live Oil within minutes and praise the product for its ability to provide relief from various conditions like pain, anxiety, and inflammation. They also appreciate the company’s commitment to quality and sustainability. Also noteworthy is the fact that Hempsi’s customer service is responsive and helpful.

  • Proprietary extraction process
  • Improved entourage effect
  • Organic and non-GMO hemp
  • Vegan-friendly ingredients
  • Third-party tested
  • Only one flavor option

How We Chose the Best CBD Oils for Pain

When determining the best CBD oils for pain, we looked at key factors that point to a quality product.

Potency (Strength of the CBD)

Potency is one of the most important things to look at when choosing CBD oil. The higher the potency, the more cannabidiol in the oil and the stronger the effects will be. However, it’s important to remember that CBD oils are not one size fits all—what works for one person may not work for another. That’s why we gave brands with a wide range of potency options higher marks in our evaluation.

The extraction method used to produce CBD oil also affects its quality. CO2 extraction is considered the gold standard, as it creates a purer product that is free of harmful solvents. However, this method is also more expensive, which is reflected in the oil price. Brands that use cheaper methods like ethanol extraction were given lower marks.

One of the best ways to gauge whether a CBD oil is effective is to read customer reviews. We looked for brands with many positive reviews and positive feedback about specific products.

We also looked for brands transparent about their manufacturing process and sourcing of hemp. Brands that made their third-party testing results available on their website received higher marks.

Of course, the most important thing we looked at was whether the CBD oils were effective. We looked at customer reviews to gauge whether people felt the oils helped with conditions like pain, anxiety, and inflammation. We also examined whether the oils had any side effects or adverse reactions.

Since you’re ingesting CBD oils, choosing a product that doesn’t contain any harmful ingredients or toxins is crucial. In addition, we looked for companies that don’t use hemp treated with herbicides or pesticides to ensure you’re not putting any nasty chemical residue into your body.

What to Consider Before Taking CBD Oils for Pain

Before taking any CBD oil, it’s essential to consult with your doctor, especially if you’re taking other medications. CBD can interact with some prescription drugs, so it’s always best to err on the side of caution.

If you’re considering taking CBD oil for pain, you should talk with your healthcare provider to determine whether it’s the right option for you. There are other ways to manage pain, like exercise, physical therapy, or over-the-counter medications.

Dosage is also vital to consider when ingesting CBD oil for pain. Start with a low dose and increase it gradually until you find the amount that works best for you.

How to Take CBD Oil for Pain

CBD oil can be taken in a variety of ways. It can be consumed orally, either by itself or added to food or drinks. It can also be applied topically to the skin. The best way to take CBD oil for pain will vary depending on the person and the condition being treated.

For most people, taking CBD oil orally will be the best way to get relief from pain. To administer CBD oil, take the dose into your mouth and hold the oil under your tongue for 30-60 seconds before swallowing. This gives the oil time to be absorbed into your bloodstream.

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Start with a low dose and gradually increase it as needed until you find the amount that works best for you. You can take CBD oil with or without food, and it can be taken with or without a drink.

If you’re taking CBD oil for pain, you can also apply it topically to the affected area. Topical application is thought to be more effective for certain types of pain, like joint pain or inflammation.

Health Benefits and Side Effects of CBD Oils

CBD oil has been shown to provide many health benefits, including but not limited to pain management. For example, in one study, CBD oil was found to be effective in treating arthritis pain. In another study, CBD oil was shown to effectively treat anxiety and depression.

Other potential health benefits of CBD oil include:

  • Reduced inflammation
  • Alleviation of cancer-related symptoms
  • Relief from neurodegenerative disorders
  • Reduction in seizure frequency

There are some potential side effects of CBD oil to be aware of, including:

  • Dry mouth
  • Drowsiness
  • Nausea
  • Anxiety
  • Diarrhea

CBD oil is generally considered safe, but it’s always best to consult your doctor before taking any new supplement.

What to Look for in CBD Oil Companies

When choosing a CBD oil company, it’s essential to look for one transparent about its manufacturing process and sources of hemp. It’s also crucial to find a company with positive customer reviews and feedback about specific products.

The most reputable brands will make their third-party testing results available on their website. This is a good indication of the quality of the products and the company’s commitment to safety and transparency.

You also want to check customer reviews on the products you’re considering buying. Some of the best CBD companies will average 4-5 stars on individual products.

Frequently Asked Questions

What is CBD oil?

CBD oil is a natural oil that is extracted from hemp plants. The oil contains CBD, or cannabidiol, which is a cannabinoid that interacts with the body’s endocannabinoid system. By interacting with the endocannabinoid system, CBD oil is thought to provide many health benefits, including pain relief, help with sleep and relaxation, relieving anxiety, and more.

How do I use CBD oil for pain? How much should I take?

CBD oil can be taken orally, either by itself or added to food or drinks, and shouldn’t cause a stomach upset. For most people, taking CBD oil orally will be the best way to get relief from pain because it’s easy to control the dosage.

To get the best results with your CBD oil, consult your doctor to get a dosage recommendation and guidance on how to use it.

If your doctor doesn’t provide any guidance, start with a low dose and increase gradually until you find the dose that works best for you. For example, start with 5 mg of CBD oil per day for a whole week. If you feel like you’re not getting the full benefits you seek at the end of the week, increase the dose by 5 mg and wait another week. Continue this process until you find the dose that’s best for you.

What’s the difference between full-spectrum, broad-spectrum, and isolate?

Full-spectrum CBD oil contains all of the compounds found in the hemp plant, including CBD, THC, terpenes, and other cannabinoids. Broad-spectrum CBD oil contains most of the compounds found in the hemp plant, but it has all of the THC removed. Isolate CBD oil (also known as pure CBD oil) contains only CBD, with all other compounds removed.

Full-spectrum CBD oil is thought to be the most effective because it contains all of the compounds that are found in hemp plants. These compounds work together to provide the maximum benefit through the entourage effect.

Broad-spectrum CBD oil is a good option for people who want the benefits of full-spectrum CBD oil without the trace amount of THC. Because it has all the other cannabinoids of the hemp plant, you will still get some benefits from the entourage effect.

Isolate CBD oil is a good option for people who want the benefits of CBD without any other compounds. This type of oil is also suitable for people who are sensitive to THC or other cannabinoids. No entourage effect will be produced since all other cannabinoids are missing, but you will still get the benefits of CBD.

Does CBD oil work for joint pain?

Yes, CBD oil can be great for joint pain and arthritis. This is because CBD oil is known to interact with the body’s endocannabinoid system, which is responsible for regulating pain. CBD oil is also a natural anti-inflammatory, so it may help reduce inflammation associated with joint pain.

Is CBD oil good for back pain?

Yes, CBD oil can be good for back pain. Back pain can have many causes, such as muscle strain, arthritis, or a pinched nerve. How much CBD will help your back pain will depend on what is causing it and the severity of the pain.

CBD oil can help reduce inflammation, which may help with back pain caused by arthritis or a muscle injury. CBD oil can also help relax muscles, which may help with back pain caused by a pinched nerve.

Can I rub CBD oil on my skin?

CBD oil can be applied topically to the skin. Your body will absorb the CBD oil through your skin and into your bloodstream.

This can be a good option for localized pain relief because it allows you to target the pain directly. CBD oil can also be added to lotions or creams for even more pain relief.

Topical CBD oil may also help reduce inflammation and redness associated with acne.

Is CBD oil or cream better for pain?

Which is better will depend on your individual needs and preferences. Some people prefer CBD oil because it’s easy to control the dosage and can be taken orally or added to food or drinks. CBD oil also benefits the entire body at once when taken orally, which might be better for widespread pain.

Many may prefer CBD oils because, in addition to relieving pain, it can help you relax and sleep, which can be hard when you’re suffering from sore joint or muscle pain.

CBD cream can be a good option for localized pain relief because it’s easy to apply and can be targeted directly to the pain. CBD cream may also be beneficial for skin conditions like acne or eczema.

If you’re not sure which is better for you, start with a small amount of both and see how you feel.

Can dogs use CBD oils for humans?

No, dogs should not use CBD oils for humans. Dogs and humans metabolize CBD differently, and CBD oil for humans is typically much more potent than CBD oil for dogs.

Furthermore, some flavoring and added ingredients to human CBD oil can be toxic to dogs. CBD oil can be great for dogs in many of the same ways it is for us. But make sure to get CBD oil specifically for dogs, and start with a very small amount to see how your dog reacts. Only CBD oils made specifically for dogs are safe for them.

Many, but not all, CBD oil brands that make products for people also have a pet range, offering CBD oils, treats, and more for dogs and cats.

How long does it take for CBD oil to kick in?

CBD oil typically begins to work within a half-hour when taken orally. However, you will feel the most benefits of CBD oil for pain after consistent use for two weeks. This is because it takes time for the CBD oil to build up in your system and work its way into providing the best benefit to your body via the endocannabinoid system.

If you don’t feel immediate pain relief, don’t give up! CBD oil is a natural remedy that may provide long-term benefits with consistent use. If you still don’t feel the benefits after two weeks, try upping your dose gradually.

How long does CBD oil last for pain relief?

When taken orally, the effects of CBD oil can last for four to six hours. Depending on their metabolism and dosing, some people might experience pain relief for a full day. Topical CBD oil may also provide longer-lasting pain management. This is because it’s absorbed directly into the skin, where it can interact with the body’s endocannabinoid system for more prolonged relief.

What’s the difference between tinctures and oils?

Tinctures and oils are both CBD products that are taken orally. Oils are made by combining CBD extract with a carrier oil, such as MCT oil or hemp seed oil. This makes them easier to consume, and they are often more potent than tinctures.

Tinctures are made by combining CBD extract with alcohol. This makes them less potent than oils, but they are still an effective way to consume CBD and often contain other beneficial ingredients like vitamins or essential oils.

What is the best CBD strain for pain?

The best CBD strain for pain will vary from person to person. Some people prefer Indica strains for pain relief because they are more relaxing. Others prefer Sativa strains because they provide more energy. Ultimately, it will depend on your individual needs and preferences. Talk to your doctor or a cannabis specialist to find the best CBD strain for you.

What concentration of CBD is good for pain?

Unfortunately, getting pain relief from CBD oil doesn’t have a one-size-fits-all answer. The concentration of CBD that’s effective for chronic pain management will vary from person to person, and you’ll most likely have to experiment a bit before you find your sweet spot.

A good starting point is 25-50 mg of CBD per day, but you may need more or less depending on your individual needs.

Does CBD oil help with inflammation?

Yes, CBD oil can help with inflammation. CBD is best known for its anti-inflammatory properties, and CBD oil works by interacting with the body’s endocannabinoid system to reduce inflammation throughout the body.

By binding with receptors in your immune system and brain cells, CBD helps reduce your body’s perception of pain by decreasing the release of inflammatory cytokines and modulating pain signals. CBD oil is a natural and effective way to reduce inflammation, and it can be used both topically and orally.

What’s the difference between hemp seed oil and CBD oil?

Hemp seed oil is made from the hemp plant’s seeds, and it does not contain any CBD or other cannabinoids that are found in the leaves of hemp plants. CBD oil is made by extracting CBD from the leaves of hemp plants, and it can contain trace amounts of THC as well as all the other beneficial cannabinoids found in cannabis plants.

CBD oil is used for medicinal purposes, and hemp seed oil is used in various industrial applications. Hemp seed oil is also sometimes used as a dietary supplement and is often used as the carrier oil in CBD oil products.

CBD Oil for Pain: Will it Work for Me?

CBD oil is a natural remedy that has been shown to be effective for pain relief. However, it is not suitable for everyone. If you’re considering CBD oil for pain relief, it’s essential to understand how it works and whether or not it’s right for you.

CBD oil can help reduce chronic pain by binding to receptors in the endocannabinoid system, which may help to decrease inflammation and provide other benefits. Some people find great relief with CBD oil, while others don’t feel any pain relief at all.

The only accurate way to know if CBD oil will work for your pain is to try it. Start with a small dose and increase gradually until you find the dosage that works best for you. You may need to experiment with different brands and potencies to find the best CBD oil for your pain.

When you first start taking CBD oil for pain, monitor yourself for any side effects and consult with your doctor if you have any concerns. CBD oil is generally considered safe, but it can interact with some medications. Do your research and talk to your doctor before taking CBD oil for pain.

CBD oil can be a great natural form of pain management, but finding the best and highest-quality product isn’t always easy. Knowing which one is right for you can be tricky with so many products on the market.

That’s why we’ve put together this list of the best CBD oils for pain, so you can decide which product is right for you. With the facts and information in this article, you’ll be able to find the best product to relieve your chronic pain. If you’re looking for a place to start, we recommend any of the CBD oils on this list.

Disclaimer: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.

Best CBD Oil for Pain Relief & Inflammation: Highest Quality Brands On The Market

Over the past three years, CBD oil has become increasingly popular as a health and wellness supplement.

One of the main reasons people are interested in trying CBD oil is because of its pain-killing benefits. We’ll get into the details of how CBD is suggested to help with pain later, along with some suggestions for the best CBD oils for pain and inflammation.

The ability for CBD to help with pain is a significant advantage over conventional pain management options — which often involve addictive and potentially harmful medications. Instead, this natural supplement has very few side effects and an exceptional safety profile — all without compromising on effectiveness.

But how do you choose the right CBD oil for the job?

This is an important question to ask because the truth of the matter is that not all CBD oils work. Many simply contain too little CBD to be of any help, while others contain harmful contaminants like heavy metals, pesticides, or chemical solvents — all of which could add to the pain you’re already experiencing by damaging the sensitive nerve cells around the body.

We’re going to cover all of this in the article below. You’ll learn how to spot a high-quality CBD oil and how current evidence shows CBD to work inside the body.

This is a big topic, so let’s get started with our list of top-rated CBD oils for pain.

Top 10 Best CBD Oil Brands for Pain Management in 2022

Not sure which CBD oil to buy to help with chronic pain? Before we get into the nitty-gritty of how CBD is suggested to work for pain and inflammation, here’s our top 5 list of CBD oils I’ve used myself for back pain.

We’ll also offer some advice on a few ways you can spot a trustworthy CBD vendor even if they didn’t quite make it onto our list.

I’ve been using CBD for over 5 years now and I’ve stumbled upon some stellar companies with top-notch oils and fly-by-night businesses with oils that can’t simply don’t work.

I have a relatively short list of CBD brands that I fully trust and I want to share my choices with you so you can avoid some of the headaches and disappointment I’ve already endured.

Here are my top 10 CBD oil brands for pain:

1. Royal CBD (Best CBD Oil On The Market)

Technical Details
Total CBD Content 250 – 2500 mg
Available Flavors Natural, Mint, Vanilla, Berry
Potency 8.3 – 83.3 mg/mL

Get 15% off all Royal CBD products. Use code “CFAH” at checkout.

Why Royal CBD is My Top Pick:

As skeptical as I am towards the majority of new CBD brands, I decided to give Royal CBD a try because I liked the company’s dedication to quality. I love seeing companies that take what they do seriously.

You can tell right away from the color, flavor, and consistency of the oil that you’re dealing with a product well above average.

This oil is cheaper than most of the other premium CBD oils I’ve tried, comes in a full range of potencies, and uses some of the best full-spectrum hemp extracts I’ve ever seen. I’ve heard friends using this brand for quite some time and decided to give it a try for myself — so I ordered a few bottles in different strengths.

After taking the Royal CBD’s 2500mg full-spectrum CBD oil for just over a week, I noticed an improvement in my back pain. There was a time when I had serious problems falling asleep because of the sharp pains in my back that seemed to intensify whenever I laid down to fall asleep. It was a nightmare. I’d lay awake for hours changing positions to try and find a spot that didn’t leave me writhing in discomfort.

With this oil, my experience went far beyond what I expected. Not only did it help ease the pain, but my overall quality of sleep improved. I mean, I didn’t sleep longer but I began to wake up rested and with a clear head.

My favorite combination for this particular oil is the vanilla in the 1000 mg bottle. This is the largest potency option currently offered by Royal CBD and has the best value overall. I took the oil twice per day, once in the morning when I woke up, and again in the evening before bed. One bottle of the 1000 mg CBD oil lasted me about a month.

  • Sourced from US-grown organic hemp
  • Extracted with supercritical CO2
  • Contains the full spectrum of cannabinoids and terpenes
  • Available in 4 different strengths
  • Up to 2500mg of CBD per bottle
  • Lab-tested for potency and purity
  • Great natural flavors (no aftertaste and comes in multiple flavor options)
  • Free shipping within the USA
  • Newer brand on the market that only sells online, no physical presence

2. Gold Bee (Best Organic CBD Oil)

  • Premium Colorado-grown hemp
  • CO2 extraction
  • Contains full-spectrum CBD
  • Delicious kiwi flavor
  • Sweetened with organic honey
  • Lab-tested for potency and purity
  • Only one flavored option available
  • No high-strength oils (yet)

What I Like About Gold Bee:

I honestly believe Gold Bee makes the best organic CBD products out there. The brand combines premium Colorado-grown hemp with organic honey sourced from the Brazillian Rainforest. While Gold Bee offers a modest selection of oils — with up to 1200 mg of CBD per bottle — the formula is spot-on when it comes to the quality of ingredients. I’m totally not going to complain about the potency, as my back pain and sleep quality got better than with some high-strength oils I’ve tried in the past. Considering the quality of these products, they actually come at a bargain price. If you want to try other formats from Gold Bee, you can choose between its high-strength capsules and CBD-infused honey.

3. CBDPure (Runner Up)

Technical Details
Total CBD Content 100 – 600 mg
Available Flavors None
Potency 1.6 – 10 mg/mL
What I Like About CBDPure CBD Oil:

I love how transparent this company is. If I were judging companies solely by their transparency level, CBDPure would have scored the second place, right after Royal CBD. The company provides all the details about each stage of production when making this CBD oil. You can find all the third-party lab test results for each batch on the product page — something we’ve come to expect from any high-quality CBD company.

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What really makes this company stand out is its incredible satisfaction guarantee. If you order the product and decide it wasn’t working for you, simply send it back and get a full refund. This satisfaction guarantee extends over 3 whole months — which is about three times longer than the industry average.

I keep a bottle or two of CBDPure oil in my medicine cabinet for achy moments after a run or hike with the kids.

The only real downside to this oil is the potency — which comes in denominations of 1.5, 5, and 10 mg/mL. This is suitable for more minor symptoms, but may not be enough for people with heavy CBD demands.

  • Sourced from Colorado-grown organic hemp
  • Extracted with supercritical CO2
  • Tested for the cannabinoid content and purity in a third-party lab
  • Rock-solid 90-day return policy
  • Narrow product range
  • Low potency
  • They don’t ship to every state (i.e. Louisiana, Indiana, Arkansas, Kansas)

4. HempBombs

Technical Details
Total CBD Content 300 – 4000 mg
Available Flavors Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon
Potency 10 – 133.3 mg/mL
What I Like About HempBombs:

I used HempBombs CBD isolate-based hemp oil for quite some time before switching to full-spectrum CBD oil and in my opinion, this is the best brand when it comes to CBD isolates. Their products contain 99% pure CBD and ZERO THC.

Now don’t get me wrong, CBD isolates are great, they offer consistent doses of CBD, contain 0% THC, and are generally cheaper than their full-spectrum counterparts. In most cases, I like using a full-spectrum extract like Royal CBD oil because of something called the entourage effect — which is a concept highlighting the phenomenon where cannabinoids like CBD tend to work better when other hemp-derived compounds are also present.

In isolates, the only cannabinoid present is CBD.

HempBombs CBD oil is available in five different strengths — from 300mg to 4000mg per bottle. The CBD is added in the form of a 99% pure isolate — which means there’s going to be virtually no traceable amounts of any other cannabinoids, including THC, CBC, CBG, or CBN.

You can also buy these oils in different flavors. Hemp Bombs often adds new flavors to the list, but my all-time personal favorite is the Acai berry. It’s not too sweet but adds a really pleasant flavor to the otherwise bland CBD and MCT oil formula.

  • Sourced from 100% certified organic hemp from European farms
  • Extracted with supercritical CO2
  • Completely THC-free
  • Tested in third-party laboratories for purity and potency
  • Available in 5 separate strengths
  • Up to 4000mg of CBD per bottle
  • Lacks the synergistic effects from other cannabinoids
  • The highest potencies are overkill for most users
  • Uses synthetic flavoring agents

5. CBDistillery

Technical Details
Total CBD Content 250 – 5000 mg
Available Flavors None
Potency 8.3 – 166 mg/mL
What I Like About CBDistillery:

CBDistillery is now one of the largest CBD companies in North America. The company began in 2016 as a legacy brand for Balanced Health Botanicals.

Over the years, CBDistillery has had the chance to really dial-in its CBD oil formula. The company now sells its CBD oil in two formats — “full-spectrum” and “THC-free.” The THC-free option is great for people who want to benefit from the synergy of CBD and other cannabinoids but without bringing any THC whatsoever into their system.

Even the full-spectrum option contains less than 0.3% THC — which is well below the amount needed to cause any psychoactive effects. These oils are both completely non-psychoactive.

You can choose between five different strengths, starting at 250mg up to 5000mg of CBD per bottle. This covers just about every range of potencies you would ever need. We recommend opting for the higher potency options because they have the best value overall. The higher potency you purchase, the further your dollar gets you.

The more potent options also las the longest because you need smaller amounts of the oil each time to get the desired dose of CBD.

I tried the 1000mg bottle to keep myself calm during the first few months after giving birth to my first son and I must admit it helped me maintain my sanity during that time. I found it to have a remarkable calming effect on the body and mind.

  • Available as full-spectrum CBD or pure CBD oil (THC-free)
  • 5 strengths to choose from
  • Carries up to 33.3 mg of CBD per mL (in the 1000 mg bottle)
  • Excellent value CBD oil
  • The hemp isn’t certified organic
  • No flavor options available
  • The company website is clunky and hard to navigate

6. NuLeaf Naturals

Technical Details
Total CBD Content 240 – 4850 mg
Available Flavors None
Potency 48.5 mg/mL
What I Like About NuLeaf Naturals

Nuleaf Naturals is one of the most popular CBD companies in the United States — most likely related to how long the company has been in the business of selling CBD. Nuleaf naturals were one of the first CBD companies to enter the mainstream market.

Despite the companies longstanding reputation, Nuleaf Naturals only sells one CBD oil. When you go to the website you’ll find a few different options, including a pet oil — but it’s important to understand that these are all the exact same full-spectrum extract, the only difference is the bottle sizes.

We love the simplicity of Nuleaf Naturals product lineup. The oils come with a decent potency of around 48 mg/mL, and just about every bottle size you can imagine. This makes it easy for everybody to find a product that works for them regardless of the budget.

With that said, if you have the cash, we highly recommend getting the larger bottle sizes in order to get the best value for your money.

You can choose between five different sizes:

  • Sourced from organic Colorado-grown hemp
  • Extracted using supercritical CO2
  • Made from a full-spectrum hemp extract
  • More expensive than the other brands in this ranking
  • Narrow product range

7. Charlotte’s Web

Technical Details
Total CBD Content 200 – 1800 mg
Available Flavors Mint Chocolate, Lemon Twist, Orange Blossom, Olive Oil
Potency 7 – 60 mg/mL

About Charlotte’s Web:

Charlotte’s Web is one of the pioneers in the American CBD industry. Established by the Stanley Brothers, the company has coined a reputation of a trustworthy manufacturer by helping now late Charlotte Figi with her treatment-resistant epilepsy. Although the company has recently received a warning letter from the FDA due to their health claims, they still have many faithful customers and a massive number of positive reviews on the web.

Charlotte’s Web CBD oil comes in several potencies: 200 mg, 500 mg, 1500 mg, and 1800 mg of CBD per bottle. The highest strength offers 60 mg of full-spectrum CBD per milliliter. There are two bottle sizes to choose from: 30 mL and 100 mL; Charlotte’s Web also has flavored variants of its CBD oil, including Lemon Twist, Orange Blossom, Mint Chocolate, and Olive Oil.

What could the company do better?

First off, they could change their extraction method because they use ethanol, which is less efficient than CO2 extraction. Secondly, and most importantly, the suspension in olive oil makes them taste a bit bitter — even in the flavored versions.

Pros:

  • One of the most reputable brands on the market
  • Full-spectrum CBD
  • Delicious flavored versions
  • Up to 1800 mg of CBD per bottle
  • Available in two sizes: 30 mL and 100 mL
  • Third-party tested for potency and purity

Cons:

  • Non-organic hemp
  • Ethanol extraction
  • Suspension in olive oil (bitter taste)
  • The company received a warning letter from the FDA in the past due to inappropriate health claims

8. cbdMD

Technical Details
Total CBD Content 300 – 7500 mg
Available Flavors Natural, Berry, Orange, Mint
Potency 10 – 250 mg/mL

About cbdMD:

cbdMD is another popular manufacturer that offers a wide range of CBD extracts, from tinctures to gummies to capsules, bath bombs, topicals, sleep aids, and pet products.

The brand offers a wide range of pure CBD oils, with up to 7500 mg of CBD per bottle. The highest potency comes with a whopping dose of 200 mg of pure CBD suspended in MCT oil for higher bioavailability and a smoother flavor. cbdMD also has three flavored CBD oils: Berry, Orange, and Mint.

Despite an impressive potency range, cbdMD uses broad-spectrum CBD in their products, which doesn’t evoke the full entourage effect. The higher potency may not necessarily mean better results in this case.

The company has high transparency standards; not only does cbdMD broadly describe their activity from farming to testing, but they also provide batch-specific certificates of analysis for their products, including the results for potency and common contaminants like pesticides, heavy metals, and residual solvents.

Pros:

  • US-grown, non-GMO hemp
  • CO2 extraction
  • THC-free
  • Up to 7500 mg of CBD per bottle
  • Batch-specific certificates of analysis

Cons:

  • Limited entourage effect due to the lack of THC
  • Most people don’t need such high doses of CBD in their routine

9. Medterra

Technical Details
Total CBD Content 500 – 3000 mg
Available Flavors Natural, Citrus, Mint Chocolate
Potency 16 – 100 mg/mL

About Medterra:

Medterra is a small craft company from California. The brand offers premium CBD oils in different spectra: full-spectrum CBD, broad-spectrum CBD, and isolates. The potency of these products ranges between 500 mg and 3000 mg of CBD per bottle, which is a standard range. On top of the unflavored version, there are two flavored options: Citrus and Chocolate

Medterra prides itself on making the real full-spectrum CBD because each bottle of its full-spectrum CBD oil comes with 2 mg of THC. However, these products are only legal in the states that have legalized higher amounts of THC for recreational use. So, if you want to buy the company’s products in all 50 states, your options are limited to broad-spectrum CBD and CBD isolate. These provide more CBD per bottle — upwards of 1000 mg.

The entire Medterra’s product range is tested in a third-party laboratory for their CBD content and safety.

Pros:

  • Premium-grade CBD oils
  • Up to 3000 mg of CBD per bottle
  • Available as full-spectrum CBD, broad-spectrum CBD, and isolates
  • Lab tested for potency and purity

Cons:

  • The “real” full-spectrum CBD oil isn’t available in all states
  • Some of the lab reports indicate higher CBD levels than stated on the bottle
  • No discounts for returning customers

10. Joy Organics

Technical Details
Total CBD Content 450 – 900 mg
Available Flavors Tranquil Mint, Fresh Lime, Summer Lemon
Potency 15 – 30 mg/mL

About Joy Organics:

Joy Organics holds the reputation of one of the most reputable CBD vendors in the industry. The company was established by a woman named Joy Smith, who has been using CBD oil to manage her problems with pain and sleep. After experiencing the benefits of CBD first-hand, she has decided to share her passion for cannabis with other health-conscious consumers.

The brand sells a range of broad-spectrum CBD products from certified organic hemp. They have many positive reviews all over the Internet; they also haven’t received any warning letter regarding health claims from the FDA — unlike many companies in this space (even the veterans like Charlotte’s Web).

The Joy Organics CBD oil features a broad-spectrum CBD formula in a modest potency range, from 450 to 900 mg of CBD per bottle. You can choose from three refreshing flavors: Summer Lemon, Fresh Lime, and Tranquil Mint. The strongest version of the Joy Organics CBD oil contains 30 mg of broad-spectrum CBD in every milliliter, which is a standard dose for most people who take CBD oil for daily supplementation.

In 2018, one of the company’s flavored CBD oils was found to contain a fungicide that is commonly sprayed on citrus fruit during independent lab testing. Fortunately, Joy Organics recalled the product shortly after this incident and implemented a new third-party testing system to make sure there are no flaws in the end product.

Pros:

  • Non-GMO, US-grown hemp
  • Supercritical CO2 extraction
  • Broad-spectrum CBD
  • THC-free
  • Delicious flavors

Cons:

  • A bit expensive
  • No high-strength oils

CBD Oil for Pain Management: Complete Guide for Beginners

Now that we’ve covered a few CBD oil options that are going to provide the best value for your money, let’s discuss how CBD is suggested to support chronic pain in the first place. We’ll also cover some of the most common ways people are using CBD oil for pain.

What is CBD Oil?

CBD stands for cannabidiol _ it’s one of the primary active ingredients in the cannabis plant. It’s completely non-psychoactive and offers a wide range of benefits to the human body.

CBD oil is a combination of a CBD extract, with a carrier oil to help dissolve and store the CBD. Most CBD oils use carrier oils like MCT oil, or hemp seed oil — which is then combined with CBD isolate, or full-spectrum hemp extract rich in CBD and other similar cannabinoids.

Cannabinoids like CBD are fat-soluble — which means they dissolve when mixed with oil, but won’t dissolve in water. By dissolving these compounds in an oil solution, the CBD becomes much easier to store and use. Instead of measuring out micrograms of CBD crystals or hemp resin, all you need to do is measure oil to get your dose of CBD. This can be done using a simple dropper that comes standard with most CBD oils.

Because of their ease of use, and long shelf-life, CBD oils have become the go-to method of using CBD and other hemp extracts.

You can also opt-out to use CBD-infused gummies if you wanted something discreetly, read our in-depth review on CBD Gummies to understand better.

How Does CBD Work?

Cannabis has been used for managing pain and inflammation for thousands of years.

The earliest records of the medical use of the herb date back to ancient China when the emperor Shen-Nung placed it among other therapeutic substances in the Chinese pharmacopeia (1). The leaves were wrapped around an injury as a poultice to reduce pain and discomfort, and reverse swelling and bruising.

Despite being a known medicine for a long time, scientists have only recently begun to unlock the mechanisms cannabis uses to achieve its important pain-killing benefits.

Since the discovery of the endocannabinoid system in 1992, CBD and other phytocannabinoids have been in the spotlight of modern medicine.

The endocannabinoid system is one of the most important neurochemical networks in the human body (2). It works by interacting with the endocannabinoid system — a series of hormones and receptors that help regulate over a dozen core processes in the human body. The active compounds in the cannabis plant are very similar to the naturally-produced hormones involved with our endocannabinoid system.

By interacting with the endocannabinoid system, CBD and other cannabinoids are able to modulate several key processes, such as:

  • Appetite
  • Immune function
  • Memory
  • Mood
  • Stress
  • Sensory perception (including pain)
  • Inflammation
  • Reproductive health
  • Nerve function
  • Sleep

How Can CBD Reduce Pain Transmission?

How does all of this relate to pain? The answer lies in the way pain is transmitted to the brain.

When we injure ourselves, cells in the immediate vicinity begin releasing compounds that trigger a cascade of inflammation and sensory activation — which is what triggers the pain transmission.

The pain signal is then sent to the spinal cord through a network of nerves distributed all around the body.

Once in the spine, the pain signal is sent through a gateway (opioid and vanilloid receptors) designed to limit the amount of signal that ends up in the brain for processing. This works like a border crossing. The border security decides whether or not you’re allowed to enter and what you can take with you.

In the context of pain, these gateways can limit the amount of pain signal that continues across the border to the brain. If more pain signal is allowed to pass, the brain perceives more pain. If the pain is stopped at the border, the brain perceives less pain.

Conventional pain medications work by activating the opioid receptors acting as a key gateway for pain transmission to the brain.

CBD has a similar effect, but through a different receptor is known as the vanilloid receptors. These vanilloid receptors are tasked with regulating a specific form of pain caused by either heat or inflammation. CBD has been reported to modulate this vanilloid receptor — leading to a reduction in the pain signals sent to the brain from inflammatory causes such as arthritis, muscle damage, or infection, to name a few.

CBD has other ways it can limit pain transmission as well:

  • CBD may reduce inflammation, limiting the initial cause of pain in the body
  • CBD acts as an antioxidant, helping the body resist and recover from damage
  • CBD relaxes muscle fibers, reducing pain caused by muscle spasms and tightness

More research is needed to fully understand how CBD and other active cannabinoids can block pain. Every year dozens of new research papers are published in an attempt to paint a clear picture of how CBD works, how to get the most benefit from the supplement, and what its limitations are.

(Pain Transmission Pathway to the Brain)

Choosing CBD Oil Companies: How to Differentiate the Good From the Bad

CBD has become a lucrative business. Companies are selling a myriad of different CBD oils and other products in an attempt to cash in on the new health trend. This means there are a lot of excellent products coming to market, but it also means there’s a lot of trash as well. It’s important as a CBD user that you understand what makes a CBD oil good, and what makes it bad so you can avoid wasting your money, or worse — using CBD oils that contain harmful or damaging ingredients.

Let’s cover the most important points to remember when looking for CBD oil online retailers.

1. Check the Hemp Source

The source of the hemp used to make the oil is vitally important when it comes to determining which CBD oils are the best. The main reason comes down to the botany of the hemp plant itself.

Hemp is a bio-accumulator — which means it has the tendency to absorb compounds from the soil and accumulate them in its leaves, stems, and roots. The deep taproots of the hemp plant stretch far beneath the soil, pulling out and storing all the heavy metals and other elements it can find in the soil.

This aspect is in part why hemp is so nutritious, but it also means that plants grown in contaminated soils often contain contaminants that can be harmful to your health. Some of the worst offenders are heavy metals — which can build up in the body over time and lead to severe long-term health effects.

You want to avoid consuming heavy metals at all costs.

Poorly grown hemp could contain heavy metals, as well as other contaminants like mycotoxins, or pesticide residues that will end up in the CBD oil after all the processing is complete.

For this reason, it’s important to purchase CBD oil from companies that account for this effect. Only buy from company’s that make an effort to source hemp from organic farms, and take measures to assess every batch of hemp that enters the facility to determine heavy metal, microbial contaminant, and pesticide contamination.

The best hemp sources tend to come from states like Oregon, Colorado, or Alabama, as well as neighboring countries like Canada or Scandinavian countries. These places are all known for having high standards for hemp cultivation, and clean soils.

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2. Look for CO2 Extracted Products

Once the company has the hemp, they need to extract the CBD from it. You can do this in many different ways using solvents like ethanol, methanol, hexane, ether, or butane. All of these solvents work to strip the active compounds from the hemp plant and can then be evaporated to leave behind a pure CBD-rich resin.

however, there’s a problem with these solvents.

Even in professional lab settings, it can be very difficult to remove all traces of these solvents from the final product. Most of these solvents are toxic to the human body, even in trace amounts.

Therefore, the best companies are using another method to strop the active ingredients from the starting hemp material. This method uses CO2 placed under high pressure. the high pressure and temperature control convert the CO2 into a phase that’s neither liquid nor gas. This special state is referred to as being supercritical.

Supercritical CO2 acts just like any other solvent, but with one key benefit — as soon as the pressure is relieved, the gas evaporates completely, leaving behind no harmful chemical residues.

when shopping for CBD oil, it’s ideal to look for a company that uses supercritical CO2 to extract the CBD rather than the toxic solvents mentioned above. Supercritical CO2 is very expensive and highly technical — but usually produces a far superior product in the end.

If a company is using harsh solvents like butane or propane (or they don’t tell you anything about their extraction methods), it’s a sign that you should look for another brand.

3. Ask for Third-Party Lab Reports

Every company has the option to send their products to an independent lab or third-party testing.

These laboratory tests check for the entire cannabinoid profile of the extract and are able to detect over 200 common contaminants.

Before a CBD product becomes available for sale, it should pass the laboratory test for potency and purity. If any inconsistencies are shown between different batches of the same product, the company should rework it and send it for analysis once again.

High-quality CBD companies will continually send each batch of product to a lab with no affiliation to the company (called a third-party or independent lab) for testing. These results are then published publicly on the website for customers to view.

The best companies will take this even one step further — adding a database and batch numbers on every bottle of CBD oil so you can view the results for your specific bottle of oil. Third-party testing is now an industry standard.

Always buy your CBD oil from companies that show third-party lab reports on their website. Only then will you know what’s inside the bottle before you even order a product. If the company is producing CBD oil that’s as high quality, as they say, there should be nothing to hide in these lab tests and they should be listed publicly on the company website. If you can’t find them on the site, you can ask customer service for these as well.

If these tests don’t exist, or you can’t track them down from the website or customer service — it’s best to avoid this company and move on to another that takes this important step seriously.

What the Research Says About Using CBD Oil for Pain:

Understanding how CBD works is no simple task. This compound is incredibly complex — working through a number of unrelated receptors around the body, interacting with enzymes, cell membranes, and various other cell structures. This makes studying CBD very difficult.

Nevertheless, there have been thousands of research papers published on medical marijuana — seeking to understand the interaction between cannabinoids like CBD and the human body. A lot of this research specifically focused on the effects of CBD on various forms and causes of pain. Let’s explore some of the results this research has yielded in the context of pain management.

1. CBD Oil for Chronic Back & Nerve Pain

The painkilling properties of cannabidiol have been most thoroughly studied in animal models, as well as a handful of human clinical trials.

One of the best studies we have available on the topic is a meta-analysis published in 2017. This analysis looked at 24 different clinical trials involving 1,334 patients over several years and demographics. These studies all used various forms of cannabis for treating chronic pain. The analysis reports that many of these studies showed a reduction in chronic pain scores by 50% or more (3) — suggesting the cannabis plant to be a potential treatment for chronic pain.

Another clinical trial looked at the effects of a combination of CBD to THC in the treatment of intractable cancer pain. This study found that twice as many people in the treatment group given CBD and THC had a 30% or more reduction in pain symptoms at the conclusion of the trial (6).

Even though more clinical trials on humans are needed to gauge how CBD affects specific forms of pain or other conditions, scientists believe the efficacy of CBD in treating chronic pain is related to its anti-inflammatory effects (3).

2. CBD Oil for Arthritis

CBD has had a lot of research as a potential alternative to prescription and non-prescription pain medications commonly used for alleviating arthritis pain.

Researchers have found a clear link between the endocannabinoid system and the pathophysiology of osteoarthritis, which is a degenerative joint disease associated with chronic pain and inflammation (4).

One of the key areas CBD is thought to support osteoarthritis specifically is through the effects on an enzyme known as 5-lipoxygenase — AKA 5-LOX. CBD has been shown to inhibit this enzyme (7), which converts fatty acids into pro-inflammatory compounds. These inflammatory messengers have been shown to be a key component in the underlying inflammation involved with osteoarthritis (8).

By reducing the underlying causes of arthritis pain, CBD is thought to reduce the overall burden of pain from the condition over the long term.

3. CBD and Multiple Sclerosis (MS) Pain

Due to its antioxidant and anti-inflammatory properties, CBD is a potent neuroprotective — which is how experts believe CBD is able to relieve debilitating MS pain, —which affects roughly 50–70% of patients diagnosed with the condition.

A study conducted on animals at Cajan Institute tested the anti-inflammatory effects of CBD on mice the researchers wanted to find out if CBD can provide a reversed inflammatory response on those cells. After ten days, the researchers found a reduction in inflammatory markers with a rodent encephalitis model designed to imitate the impact MS has on the body (5).

More research is needed to see exactly how these effects are translated to humans. Currently, there are 23 clinical trials currently underway, or planned within the next 12 months seeking to explore the effects of CBD on MS.

4. CBD Oil in Sports: Injuries & Muscle Endurance

Cannabidiol can be applied in two different ways when it comes to pain and physical activities. For example, when you administer CBD orally in the form of oil as a post-workout, it helps alleviate the muscle inflammation that troubles athletes once they go beyond the edge again.

If, however, you’re suffering from an injury, it’s best to apply CBD topically. Its anti-inflammatory and neuroprotective properties allow the cannabinoid to relieve pain and improve regeneration capacities.

Does CBD Have Any Side Effects?

The main reason why parents are so enthusiastic about CBD is that this cannabinoid is completely non-intoxicating, doesn’t cause addiction, and has only a few mild side effects when taken at excessive doses.

Research shows that even doses up to one and a half grams have no severe side effects on human health (9).

Despite being a notoriously safe supplement, there are some side effects of using CBD in high doses. Let’s cover the most common side effects people report from using CBD:

  • Anxiety
  • Brain fog
  • Reduced appetite
  • Mood changes
  • Diarrhea or constipation
  • Dizziness or lightheadedness
  • Drowsiness or fatigue
  • Dry mouth
  • Nausea and vomiting

The most common side effect by far, like other forms of cannabis, is dry mouth. This is best managed by taking your CBD oil along with some juice like pineapple or orange juice.

Another common side effect is lowered blood pressure, which may trigger another unwanted reaction — lightheadedness. This side effect is important to consider if you suffer from low blood pressure already or are taking blood pressure-lowering medications.

Always consult your doctor before using CBD or other cannabis extracts if you’re taking prescription medications or have underlying medical conditions.

In Summary: Buying CBD Oil For Pain

As CBD becomes more popular around the world, scientists are publishing new research on cannabinoids on a near-weekly basis. As time goes on, experts are mapping out the complicated mechanisms CBD and other hemp derivatives are using to support both acute and chronic pain of all different origins.

Here are the main takeaways from the current research:

  • CBD inhibits inflammation at several different levels
  • CBD offers antioxidant support
  • CBD may relieve muscle tension and inflammation
  • CBD interacts with the vanilloid receptors in the brain responsible for regulating inflammatory pain transmission

When it comes to pain, CBD appears to target the cause of the problem instead of just masking its symptoms.

Getting relief on so many levels and without any harmful side effects or risk of addiction is the reason why CBD oil has become so popular over the past half a decade.

I hope this guide has managed to clear up any confusion regarding CBD oil and pain, and given you the insight necessary to find the right CBD oil for the job.

Have you tried CBD oil for chronic pain? Did you feel any difference? Let me know in the comments below!

References:

  1. Brand, E. J., & Zhao, Z. (2017). Cannabis in Chinese Medicine: Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids?. Frontiers in pharmacology, 8, 108.
  2. Alger B. E. (2013). Getting high on the endocannabinoid system. Cerebrum: the Dana forum on brain science, 2013, 14.
  3. Aviram, J., Samuelly-Leichtag, G. (2017) Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pain Physician, 20(6), E755-E796.
  4. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland), 23(10), 2478.
  5. Elliott, D. M., Singh, N., Nagarkatti, M., & Nagarkatti, P. S. (2018). Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Frontiers in immunology, 9, 1782.
  6. Johnson, J. R., Burnell-Nugent, M., Lossignol, D., Ganae-Motan, E. D., Potts, R., & Fallon, M. T. (2010). Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain. Journal of pain and symptom management, 39(2), 167-179.
  7. Takeda, S., Usami, N., Yamamoto, I., & Watanabe, K. (2009). Cannabidiol-2′, 6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. Drug Metabolism and Disposition.
  8. Lascelles, B. D. X., King, S., Roe, S., Marcellin‐Little, D. J., & Jones, S. (2009). Expression and activity of COX‐1 and 2 and 5‐LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis. Journal of orthopaedic research, 27(9), 1204-1208.Chicago
Nina Julia

Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.

How To Use CBD To Help Manage Pain

Dr. Bindiya Gandhi is an integrative medicine physician with expertise in functional and holistic medicine based in Atlanta, Georgia.

Commissions we earn from partner links on this page do not affect our opinions or evaluations. Our editorial content is based on thorough research and guidance from the Forbes Health Advisory Board.

Table of Contents

  • CBD for Pain Relief
  • CBD for Chronic Pain
  • CBD for Arthritis and Joint Pain
  • CBD for Neuropathic Pain

Without the intoxicating properties of its cousin delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD) can provide the human body with a handful of health benefits. Cannabinoids like CBD interact with receptors in the endocannabinoid system, which plays a role in signaling bodily functions, from emotional responses to motor control to energy balance [1] Mouslech Z, Valla V. Endocannabinoid system: An overview of its potential in current medical practice. Neuro Endocrinol Lett. 2009;30(2):153-179. .

Over the last two decades, scientists have tested CBD’s efficacy as an analgesic, or painkiller, specifically—and with promising results. While research is ongoing, here’s what we know so far about how we can use CBD oil for pain relief.

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CBD for Pain Relief

For now, no CBD-based medications are approved as painkillers in the U.S. Epidiolex, which is used for rare forms of epilepsy, is the only CBD treatment approved by the Food and Drug Administration (FDA).

Meanwhile, several countries have approved CBD to treat certain conditions. For instance, the U.K. approved it for multiple sclerosis, and Canada approved it for cancer pain. Ongoing research suggests CBD oil for pain can aid medical conditions, including arthritis and fibromyalgia, at varying doses. Some pain may not be treatable by CBD alone, but it can help when paired with THC or Western medication applications.

Interestingly, 60% of U.S. adults who use CBD products do so for its potential pain-relieving effects, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.

What’s more, 60% of U.S. adults have tried CBD and believe it has medicinal benefits.

CBD for Chronic Pain

Chronic pain is defined as any pain lasting longer than several months. Studies have found CBD, often alongside THC, to be an effective pain reliever for various chronic conditions.

In clinical trials, Sativex, a spray with equal parts CBD and THC, proved significantly successful as an analgesic for cancer-related pain [2] Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. . The spray, also used for multiple sclerosis-related pain, is approved in Canada to treat cancer pain and is currently undergoing trials for approval and use in the U.S.

A 2019 study found Sativex to be an “effective and well-tolerated add-on treatment” for patients with severe chronic pain stemming from various ailments. The study identified three types of pain: nociceptive (affecting body tissue), neuropathic (affecting nerves) and mixed pain. Sativex helped treat all three kinds but proved especially effective against neuropathic pain.

An earlier study also found CBD to be effective in chronic pain relief for conditions like multiple sclerosis and spinal cord injury, although across a much smaller sample size [4] Wade DT, Robson P, House H, Makela P, Aram J. A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Clin Rehabil. 2003;17(1):21-29. .

CBD for Arthritis and Joint Pain

Arthritis is a broad term that encompasses hundreds of joint-related conditions and pains. Common symptoms include swelling, pain and stiffness in the joints and may progress over time.

Already a proven analgesic for other conditions, CBD shows promise as an anti-inflammatory substance in both animal and preclinical trials, which bodes well for arthritis treatment [5] Nichols JM, Kaplan BLF. Immune Responses Regulated by Cannabidiol. Cannabis Cannabinoid Res. 2020;5(1):12-31. [6] Mlost J, Bryk M, Starowicz K. Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action. Int J Mol Sci. 2020;21(22):8870. [7] Kosgodage US, Mould R, Henley AB, et al. Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Front Pharmacol. 2018;9:889. [8] Lowin T, Tingting R, Zurmahr J, Classen T, Schneider M, Pongratz G. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death Dis. 2020;11(8):714. . However, clinical research dedicated to CBD administration for arthritis is less robust and ongoing.

The first controlled trial conducted in 2006 focused on patients with rheumatoid arthritis, an autoimmune disease that causes inflammation in the joints and other affected areas [9] Blake DR, Robson P, Ho M, Jubb RW, McCabe CS. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford). 2006;45(1):50-52. . Researchers found that, compared to a placebo, Sativex significantly improved participants’ pain during movement, pain at rest and quality of sleep. Any adverse reactions to the treatment were mild or moderate, and there were no complications with withdrawal.

In 2018 researchers tested the efficacy of topical CBD gel on participants with osteoarthritis-related knee pain over the course of 12 weeks [10] Hunter D, Oldfield G, Tich N, Messenheimer J, Sebree T. Synthetic transdermal cannabidiol for the treatment of knee pain due to osteoarthritis. Osteoarthritis and Cartilage. 2018;26:S26. . Participants used either 250 milligrams or 500 milligrams, split into two applications, daily. Overall, participants’ weekly pain levels didn’t improve much with CBD compared to placebo. However, when researchers evaluated the average weekly worst pain scores and Western Ontario and McMaster Universities Arthritis Index (WOMAC) physical function scores, participants who applied 250 milligrams of CBD daily experienced significant improvement over placebo participants.

Meanwhile, a small 2019 trial suggests a mix of CBD and THC may prove beneficial for people with fibromyalgia, a type of arthritis that results in whole-body pain and fatigue [11] van de Donk T, Niesters M, Kowal MA, Olofsen E, Dahan A, van Velzen M. An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia. Pain. 2019;160(4):860-869. . The study found that, via a single inhalation, a CBD-THC solution performed better than a placebo and either substance on its own.

CBD for Neuropathic Pain

Various conditions and injuries that damage nerves or the nervous system can result in neuropathic pain. This kind of pain manifests as tingling, numbness, muscle weakness and a sharp, shooting, burning or stabbing pain.

Multiple sclerosis (MS) is a common cause of neuropathic pain. The disease wears down myelin, a mixture of proteins and phospholipids that coats nerve cells. Sativex is already approved as an MS treatment around the world due to its success in clinical trials. As a spray, Sativex is absorbed in the mouth. Studies support a median dose of eight sprays a day for patients with MS, which provides about 20 milligrams of CBD and 21.6 milligrams of THC [12] Sativex Oromucosal Spray – Summary of Product Characteristics (SmPC). Datapharm. Accessed 7/9/2021. . However, doses vary between patients, and each person needs to find their optimal dose.

A 2020 study also tested topically administered CBD oil as a treatment for patients with peripheral neuropathy, or damage to the peripheral nervous system, which sends information throughout your body from the central nervous system [13] Xu DH, Cullen BD, Tang M, Fang Y. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities. Curr Pharm Biotechnol. 2020;21(5):390-402. . When compared to placebo, the topical CBD significantly reduced patients’ intense pain and sharp pain, as well as cold and itchy sensations.

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